vanA-containing Enterococcus faecium susceptible to vancomycin and teicoplanin because of major nucleotide deletions in Tn1546
نویسندگان
چکیده
منابع مشابه
Outbreak of vancomycin-susceptible Enterococcus faecium containing the wild-type vanA gene.
Accurate detection of vancomycin-resistant enterococci (VRE) is essential in preventing transmission in health care settings. Chromogenic media are widely used for screening VRE because of fast turnaround times (TAT) and high sensitivity. We report an outbreak of Enterococcus faecium bearing vanA yet susceptible to vancomycin (vancomycin-variable Enterococcus [VVE]). Between October 2009 to Mar...
متن کاملHeteroresistance to teicoplanin in Enterococcus faecium harboring the vanA gene.
Hospital-acquired infections caused by vancomycin-resistant enterococci (VRE) are increasing. The resistance of VRE to multiple antibiotics makes them clinically challenging. There are at least six phenotypes of VRE, including VanA, VanB, VanC, VanD, VanE, and VanG (2, 8). These phenotypes correspond with the genotypes vanA, vanB, vanC, vanD, vanE, and vanG. VanA and VanB phenotypes are common ...
متن کاملTransferable vancomycin and teicoplanin resistance in Enterococcus faecium.
Enterococcus faecium BM4165 and BM4178, isolated from immunocompromised patients, one treated with vancomycin, were inducibly resistant to high levels of the glycopeptide antibiotics vancomycin and teicoplanin but susceptible to the new lipopeptide daptomycin (LY146032). Strain BM4165 was also resistant to macrolidelincosamide-streptogramin B-type (MLS) antibiotics. The genes conferring resista...
متن کاملGenetic characteristics of VanA-type vancomycin-resistant Enterococcus faecalis and Enterococcus faecium in Cuba
VanA-type vancomycin-resistant enterococci isolates from bloodstream infections in Cuba were genetically characterized. Enterococcus faecalis isolates were assigned to sequence type (ST) 28, closely related to Eastern Europe, while Enterococcus faecium belonged to ST262, ST656 and ST1349, and showed different genetic profiles.
متن کاملPresence of virulence factors in Enterococcus faecalis and Enterococcus faecium susceptible and resistant to vancomycin
Despite the increasing importance of Enterococcus as opportunistic pathogens, their virulence factors are still poorly understood. This study determines the frequency of virulence factors in clinical and commensal Enterococcus isolates from inpatients in Porto Alegre, Brazil. Fifty Enterococcus isolates were analysed and the presence of the gelE, asa1 and esp genes was determined. Gelatinase ac...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2011
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/dkr379